Web Reference: CATASTROPHIC definition: of the nature of a catastrophe, or disastrous event; calamitous. See examples of catastrophic used in a sentence. The meaning of CATASTROPHE is a momentous tragic event ranging from extreme misfortune to utter overthrow or ruin. How to use catastrophe in a sentence. Did you know? If you describe something as catastrophic, you mean that it is very bad or unsuccessful. ...another catastrophic attempt to wrest control from a rival Christian militia. His mother's untimely death had a catastrophic effect on him.
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